Dr. Anton Liopo
Senior Scientist - Nanobiotechnology
Work Description:
Nanoparticle
Applications for In Vivo Molecular Targeting and Nanobase Contrast
Agent Development for Cellular
Interactions.
Contact:
al@tomowave.com
281-888-9542
Bios
Anton Liopo has a PhD in biology (emphasis on animal and human physiology). He has research experience in areas of biochemistry, neurobiology and physiology of alcohol addictions and analysis of morphology and structure changes of neuronal membranes by atomic force microscopy. For the last ten years, Anton was focused on investigation of functionalized nanoparticles, which included single-walled carbon nanotubes, polymeric nanoparticles, gold nanorods and their use for biomedical applications. In TomoWave Lab. Anton’s responsibilities are research and developing novel methodsof conjugations between bioactive molecules and high light absorption nanoparticles from different materials, shapes and constructions for cancer therapy, molecular and optoacoustic imaging and sensing.
Selected Peer Reviewed Articles
1. Liopo A., Conjusteau A., Tsyboulski D., Ermolinsky B., Kazansky A. Oraevsky A.. Biocompatible gold nanorod conjugates for preclinical biomedical research. J Nanomed. Nanotechnol. 2012, S2:001-010
2. Su R., Ermilov S.A., Liopo A.V., Oraevsky A.A. Three-dimensional optoacoustic imaging as a new noninvasive technique to study long-term biodistribution of optical contrast agents in small animal models, J. Biomed. Opt. 2012, 17, 10: 101506
3. Liopo A. V., Conjusteau A., Chumakova O. V., Ermilov S.A., Su R., Oraevsky A.A. Highly purified biocompatible gold nanorods for contrasted optoacoustic imaging of small animal models. Nanosci. Nanotech. Lett. 2012, 4, 7: 861-866
4. Liopo A.V., Conjusteau A., Konopleva M., Andreeff M., Oraevsky A.A. Laser nanothermolysis of human leukemia cells using functionalized plasmonic nanoparticles. Nano Biomed. Eng. 2012, 4, 2: 66-7
5. Atasheva S., Krendelchtchikova V., Liopo A., Frolova E., Frolov I. Interplay of acute and persistent infections caused by Venezuelan Equine Encephalitis Virus encoding mutated capsid protein. J. Virology. 2010, 84, 19: 10004–10015
6. Eghtedari M., Liopo A.V., Copland J.A., Oraevsky A.A., Motamedi M. Engineering of Hetero-Functional Gold Nanorods for the in vivo Molecular Targeting of Breast Cancer Cells. Nano Letters, 2009, 9, 1: 287-291
7. Chumakova O.V., Liopo A.V., Andreev V.G., Cicenaite I, Evers B.M., Chakrabarty S., Pappas T.C. Esenaliev R.O. Composition of PLGA and PEI/DNA nanoparticles improves ultrasound-mediated gene delivery in solid tumors in vivo, Cancer Letters. 2008, 261, 2:215–225
8. Gheith M.K., Pappas T.C., Liopo A.V., Sinani V.A., Shim B.S., Motamedi M., Wicksted J.P. and Kotov N.A. Stimulation of neural cells by lateral currents in conductive layer-by-layer films of single-walled carbon nanotubes. Advanced Materials. 2006, 18, 22: 2975 – 207
9. Liopo A.V., Stewart M.P., Hudson J., Tour J.M., and Pappas T.C. Biocompatibility of native and functionalized single-walled carbon nanotubes for neuronal interface. J. Nanosci. Nanotechnol. 2006, 6, 5: 1365–1374
10. Chumakova O.V., Liopo A.V., B. Evers M., Esenaliev R.O. Effect of 5-fluorouracil, optison and ultrasound on MCF-7 cell viability. Ultrasound Med. Biol., 2006, 32, 5: 751-758
11. Slyshenkov S, Shevalye AA, Liopo AV, Wojtczak L. Protective role of L-methionine against free radical damage of rat brain synaptosomes. Acta Biochim Pol. 2002, 49, 4: 907-916
12. Liopo A.V., Andreyeva A.L., Stukalov O. M., Chumakova O.V. (2002) AFM contact mode for imaging of synaptosomal membrane modificated by acetaldehyde. Phys. Low-Dim. Struct, 5/6: 105–113.
13. Liopo A.V., Chumakova O.V., Zavodnik I.B., Andreeva A.L., Bryszewska M., Chizhik S.A. The response of the neuronal membrane to acetaldehyde treatment. Cell Mol Biol Letters. 2001, 6, 2A: 265-269
14. Chumakova O.V., Liopo A.V., Chizhik S.A., Tayurskaya V.V., Gerashchenko L.L., Komkov O.Y. Effects of ethanol and acetaldehyde on isolated nerve ending membranes: study by atomic-forced microscopy. Bull Exp Biol Med. 2000, 130, 9: 356 –359
15. Zimatkin S.M., Liopo A.V., Deitrich R.D. Oxidation of ethanol to acetaldehyde in brain and possible behavioral consequences. Adv. Exp. Med. Biol. 1999, 463, 7: 231-236
16. Zimatkin S.M., Liopo A.V., Deitrich R.A. Distribution and kinetics of ethanol metabolism in rat brain. Alcohol: Clin. and Exp. Res.1998, 22, 8: 1623-1627
17. Liopo A.V., Omelianchik M.S., Chumakova O.V. Effects of low – dose ethanol on rat progeny upon inhalation exposure during gestation. Bulletin Exp. Biol. Med. 1996, 121, 3: 244-246.
18. Chumakova O.V., Liopo A.V. Acetylcholinesterase and choline uptake in striatum from rats with varying sleeping times. Alcohol Alcohol. 1996, 31, 2: 217-220
19. Liopo A. V., Chumakova O. V., Chirkov A. M. Evaluation of effects of chronic alcohol intoxication and withdrawal in monkeys. Scand. J. Lab. Anim. Sci. 1996, 23, 1: 449-453
Other Publications
1. Liopo A.V., Zimatkin S.M., Zakharov O.Yu. 2003, R.B. Patent N 19990772. Method determination of metabolism ethanol in brain of animals.
2. Liopo A.V., Chumakova O.V., Chizhik S.A. Atomic-force microscopy in estimation of the state of synaptosomal membrane. 2002, Minsk, Belarus: Publishing Center of Belarusian State University: 144 p. (Book)
Copyright (c) TomoWave Laboratories, Inc. 2012